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Vol 76, No 5 (2018)
Original articles
Published online: 2018-01-19
Submitted: 2017-11-29
Accepted: 2018-01-18
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EQ-5D studies in cardiovascular diseases in eight Central and Eastern European countries: a systematic review of the literature

Paulina Batóg, Fanni Rencz, Márta Péntek, László Gulácsi, Krzysztof J. Filipiak, Valentina Prevolnik Rupel, Judit Simon, Valentin Brodszky, Petra Baji, Jakub Závada, Guenka Petrova, Alexandru Rotar, Dominik Golicki
DOI: 10.5603/KP.a2018.0033
·
Kardiol Pol 2018;76(5):860-870.

open access

Vol 76, No 5 (2018)
Original articles
Published online: 2018-01-19
Submitted: 2017-11-29
Accepted: 2018-01-18

Abstract

Background:

The measurement of health-related quality of life (HRQoL) by validated generic instruments, such as EQ-5D, has become an increasingly important tool for the assessment of health care in a wide range of diagnoses.
Aim: We aimed to systematically review EQ-5D literature on cardiovascular diseases in eight Central and Eastern European (CEE) countries.


Methods:

A structured literature search was conducted in MEDLINE, EMBASE, Web of Science, CINAHL, PsycINFO, Cochrane Library, and the EuroQol website up to November 2016. Original cardiovascular-related studies that reported EQ-5D results were included.


Results:

Of the 36 papers, 17 reported EQ-5D index scores. Most studies were performed in Poland (n = 24, 67%). The most common diagnosis regarding the number of publications and population size was ischaemic heart disease (n = 13, N = 6394), followed by atrial fibrillation (n = 4, N = 1052). The average EQ-5D index scores ranged from 0.61 to 0.88 and from 0.66 to 0.95 for patients before and after cardiac procedure/surgery, respectively (including angioplasty, coronary artery bypass grafting, ablation, surgical correction of septal defects, transcatheter aortic valve implantation [TAVI]). In all studies baseline scores were lower than the repeated assessments after the procedure, with the most substantial improvement of 0.24 in high-risk elderly patients after TAVI. Studies which did not assess invasive treatment reported mean EQ-5D index scores ranging from 0.18 to 0.80.


Conclusions:

The number of cardiovascular-related studies reporting HRQoL using EQ-5D has consistently increased in CEE countries over the past decade and is outstanding compared with other clinical fields. The EQ-5D index and EQ VAS scores varied based on the disease severity, patient characteristics, and treatment protocol.

Abstract

Background:

The measurement of health-related quality of life (HRQoL) by validated generic instruments, such as EQ-5D, has become an increasingly important tool for the assessment of health care in a wide range of diagnoses.
Aim: We aimed to systematically review EQ-5D literature on cardiovascular diseases in eight Central and Eastern European (CEE) countries.


Methods:

A structured literature search was conducted in MEDLINE, EMBASE, Web of Science, CINAHL, PsycINFO, Cochrane Library, and the EuroQol website up to November 2016. Original cardiovascular-related studies that reported EQ-5D results were included.


Results:

Of the 36 papers, 17 reported EQ-5D index scores. Most studies were performed in Poland (n = 24, 67%). The most common diagnosis regarding the number of publications and population size was ischaemic heart disease (n = 13, N = 6394), followed by atrial fibrillation (n = 4, N = 1052). The average EQ-5D index scores ranged from 0.61 to 0.88 and from 0.66 to 0.95 for patients before and after cardiac procedure/surgery, respectively (including angioplasty, coronary artery bypass grafting, ablation, surgical correction of septal defects, transcatheter aortic valve implantation [TAVI]). In all studies baseline scores were lower than the repeated assessments after the procedure, with the most substantial improvement of 0.24 in high-risk elderly patients after TAVI. Studies which did not assess invasive treatment reported mean EQ-5D index scores ranging from 0.18 to 0.80.


Conclusions:

The number of cardiovascular-related studies reporting HRQoL using EQ-5D has consistently increased in CEE countries over the past decade and is outstanding compared with other clinical fields. The EQ-5D index and EQ VAS scores varied based on the disease severity, patient characteristics, and treatment protocol.

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Keywords

health-related quality of life, EQ-5D, cardiovascular diseases, ischaemic heart disease, Central and Eastern Europe

Supplementary Files (7)
EQ-5D index and EQ VAS mean scores for patients before cardiac procedure/surgery
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EQ-5D index and EQ VAS mean scores for patients with cardiovascular disease who do not undergo invasive treatment
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Distribution of limitations within Self-Care dimension of the EQ-5D
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180KB
Distribution of limitations within Usual Activities dimension of the EQ-5D
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201KB
Distribution of limitations within Pain/Discomfort dimension of the EQ-5D
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210KB
Distribution of limitations within Anxiety/Depression dimension of the EQ-5D
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203KB
Supplementary Table 1. Summary of the EQ-5D index scores in the cardiac intervention/surgery subgroups
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About this article
Title

EQ-5D studies in cardiovascular diseases in eight Central and Eastern European countries: a systematic review of the literature

Journal

Kardiologia Polska (Polish Heart Journal)

Issue

Vol 76, No 5 (2018)

Pages

860-870

Published online

2018-01-19

DOI

10.5603/KP.a2018.0033

Bibliographic record

Kardiol Pol 2018;76(5):860-870.

Keywords

health-related quality of life
EQ-5D
cardiovascular diseases
ischaemic heart disease
Central and Eastern Europe

Authors

Paulina Batóg
Fanni Rencz
Márta Péntek
László Gulácsi
Krzysztof J. Filipiak
Valentina Prevolnik Rupel
Judit Simon
Valentin Brodszky
Petra Baji
Jakub Závada
Guenka Petrova
Alexandru Rotar
Dominik Golicki

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