open access

Vol 76, No 1 (2018)
Original articles
Published online: 2017-08-21
Submitted: 2017-03-18
Accepted: 2017-07-18
Get Citation

The relationship between exposure to hepatitis B virus and increased atherosclerosis-associated morbidity — a meta-analysis

Chen-guang Li, Song-jie Liao, Jia-li Que, Ke-jia Liu, Hao-yue Wang, Jian Yu
DOI: 10.5603/KP.a2017.0165
·
Kardiol Pol 2018;76(1):119-124.

open access

Vol 76, No 1 (2018)
Original articles
Published online: 2017-08-21
Submitted: 2017-03-18
Accepted: 2017-07-18

Abstract

Background and aim: The relationship between exposure to hepatitis B virus (HBV) and atherosclerosis-associated disease morbidity has not been clearly elucidated. We performed a meta-analysis to explore whether exposure to HBV is a risk factor for atherosclerosis-associated diseases. Methods: We searched the PubMed, Web of Science, Cochrane Library, Embase, and Scopus databases for related studies. We then chose the eligible studies for meta-analysis and assessed quality assessment and risk of bias. Results: The meta-analysis of the included studies showed that exposure to HBV tends to increase atherosclerosis-associated disease morbidity, but this increase was not statistically significant. Conclusions: Hepatitis B virus may not be a risk factor for atherosclerosis-associated diseases, but further studies that employ more sensitive clinical parameters are needed to verify this result.

Abstract

Background and aim: The relationship between exposure to hepatitis B virus (HBV) and atherosclerosis-associated disease morbidity has not been clearly elucidated. We performed a meta-analysis to explore whether exposure to HBV is a risk factor for atherosclerosis-associated diseases. Methods: We searched the PubMed, Web of Science, Cochrane Library, Embase, and Scopus databases for related studies. We then chose the eligible studies for meta-analysis and assessed quality assessment and risk of bias. Results: The meta-analysis of the included studies showed that exposure to HBV tends to increase atherosclerosis-associated disease morbidity, but this increase was not statistically significant. Conclusions: Hepatitis B virus may not be a risk factor for atherosclerosis-associated diseases, but further studies that employ more sensitive clinical parameters are needed to verify this result.
Get Citation

Keywords

hepatitis B virus, atherosclerosis, meta-analysis

About this article
Title

The relationship between exposure to hepatitis B virus and increased atherosclerosis-associated morbidity — a meta-analysis

Journal

Kardiologia Polska (Polish Heart Journal)

Issue

Vol 76, No 1 (2018)

Pages

119-124

Published online

2017-08-21

DOI

10.5603/KP.a2017.0165

Bibliographic record

Kardiol Pol 2018;76(1):119-124.

Keywords

hepatitis B virus
atherosclerosis
meta-analysis

Authors

Chen-guang Li
Song-jie Liao
Jia-li Que
Ke-jia Liu
Hao-yue Wang
Jian Yu

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