open access

Vol 75, No 9 (2017)
Original articles
Published online: 2017-05-18
Submitted: 2016-10-25
Accepted: 2017-04-19
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Renal artery sympathetic nerve radiofrequency denervation

Krzysztof Bartuś, Jerzy Sadowski, Bogusław Kapelak, Radosław Litwinowicz, Jakub Podolec, Magdalena Bartuś, Artur Dziewierz, Stanisław Bartuś, Wojciech Zajdel, Dhanunjaya Lakkireddy
DOI: 10.5603/KP.a2017.0100
·
Kardiol Pol 2017;75(9):899-906.

open access

Vol 75, No 9 (2017)
Original articles
Published online: 2017-05-18
Submitted: 2016-10-25
Accepted: 2017-04-19

Abstract

Background: Arterial hypertension is one of the most common chronic diseases in the western world, affecting more than 25% of the adult population.

Aim: The aim of this study was to assess changes in arterial blood pressure (BP) levels in hypertensive patients, after ablation of nerve terminals in renal arteries, using radiofrequency energy during 24 months of follow-up.

Methods: Thirty-two patients with diagnosed resistant hypertension (20 men and 12 women) underwent percutaneous catheter-based renal denervation of nerve terminals in renal artery walls. Mean BP value before ablation was [mm Hg]: systolic 174.92, diastolic 99.73 and pulse pressure 75.19. After procedure reduction value of BP was reported [mm Hg]: systolic 146.78; diastolic 87.14, pulse pressure 59.64 at 24-month follow-up (p < 0.05 for all).

Results: 30% of patients had systolic BP ≤ 140 mm Hg, 67% had diastolic BP ≤ 90 mm Hg, and optimum BP values ≤ 140/90 mm Hg were observed in 30% of patients.

Conclusions: In our cohort of patients, percutaneous renal artery ablation procedure effectively reduces systolic, diastolic BP and pulse pressure. No adverse events during 24 months of follow-up were noted. These results were comparable with available data from SIMPLICITY I and II trials.

Abstract

Background: Arterial hypertension is one of the most common chronic diseases in the western world, affecting more than 25% of the adult population.

Aim: The aim of this study was to assess changes in arterial blood pressure (BP) levels in hypertensive patients, after ablation of nerve terminals in renal arteries, using radiofrequency energy during 24 months of follow-up.

Methods: Thirty-two patients with diagnosed resistant hypertension (20 men and 12 women) underwent percutaneous catheter-based renal denervation of nerve terminals in renal artery walls. Mean BP value before ablation was [mm Hg]: systolic 174.92, diastolic 99.73 and pulse pressure 75.19. After procedure reduction value of BP was reported [mm Hg]: systolic 146.78; diastolic 87.14, pulse pressure 59.64 at 24-month follow-up (p < 0.05 for all).

Results: 30% of patients had systolic BP ≤ 140 mm Hg, 67% had diastolic BP ≤ 90 mm Hg, and optimum BP values ≤ 140/90 mm Hg were observed in 30% of patients.

Conclusions: In our cohort of patients, percutaneous renal artery ablation procedure effectively reduces systolic, diastolic BP and pulse pressure. No adverse events during 24 months of follow-up were noted. These results were comparable with available data from SIMPLICITY I and II trials.

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Keywords

hypertension, resistant hypertension, renal artery ablation

About this article
Title

Renal artery sympathetic nerve radiofrequency denervation

Journal

Kardiologia Polska (Polish Heart Journal)

Issue

Vol 75, No 9 (2017)

Pages

899-906

Published online

2017-05-18

DOI

10.5603/KP.a2017.0100

Bibliographic record

Kardiol Pol 2017;75(9):899-906.

Keywords

hypertension
resistant hypertension
renal artery ablation

Authors

Krzysztof Bartuś
Jerzy Sadowski
Bogusław Kapelak
Radosław Litwinowicz
Jakub Podolec
Magdalena Bartuś
Artur Dziewierz
Stanisław Bartuś
Wojciech Zajdel
Dhanunjaya Lakkireddy

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