open access

Vol 68, No 9 (2010)
Original articles
Published online: 2010-09-21
Submitted: 2012-12-28
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Prevalence of classical risk factors in Polish women with premature coronary artery disease

Barbara Lubiszewska, Ewa Skóra, Mariusz Kruk, Grażyna Broda, Ewa Księżycka, Paweł Kurjata, Tomasz Zieliński, Rafał Płoski
Kardiol Pol 2010;68(9):1032-1037.

open access

Vol 68, No 9 (2010)
Original articles
Published online: 2010-09-21
Submitted: 2012-12-28

Abstract


Background: It is generally believed that in 50% of perimenopausal women several factors other than classical risk factors play a significant role in the development of premature coronary artery disease (CAD).
Aim: To determine the prevalence of five classical risk factors (cigarette smoking, hypertension, diabetes, hyperlipidaemia and obesity) in women aged < 55 years with premature CAD.
Methods: We performed a single-centre, case-control study in women < 55 years with angiographically confirmed CAD or troponin-positive acute coronary syndrome. A total of 330 female patients were enrolled between April 2005 and January 2008. The control group consisted of 347 age-matched healthy women from a similar region selected from the National Health Survey WOBASZ study (Polish Multi-centre Population Health Survey) designed to assess the cardiovascular risk in the Polish adult population.
Results: Compared to age-matched healthy controls, women with premature CAD had a very high prevalence of traditional risk factors - hypercholesterolaemia (82% vs 68%), smoking (current and former) (81% vs 48%), and hypertension (68% vs 42%). Women with premature CAD had 4.3 times more often diabetes, 1.68 times smoking and 1.63 times hypertension compared to controls. At least one of five classical risk factors was present in 98.8% of patients, compared to 89% in controls, while 10% of patients vs 1.4% of controls had all five of them.
Conclusions: Classical risk factors are present in the vast majority of females with premature CAD - in 99% of them at least one CAD risk factor is present. Premature CAD is most frequently associated with smoking, hypertension and hyperlipidaemia.
Kardiol Pol 2010; 68, 9: 1032-1037

Abstract


Background: It is generally believed that in 50% of perimenopausal women several factors other than classical risk factors play a significant role in the development of premature coronary artery disease (CAD).
Aim: To determine the prevalence of five classical risk factors (cigarette smoking, hypertension, diabetes, hyperlipidaemia and obesity) in women aged < 55 years with premature CAD.
Methods: We performed a single-centre, case-control study in women < 55 years with angiographically confirmed CAD or troponin-positive acute coronary syndrome. A total of 330 female patients were enrolled between April 2005 and January 2008. The control group consisted of 347 age-matched healthy women from a similar region selected from the National Health Survey WOBASZ study (Polish Multi-centre Population Health Survey) designed to assess the cardiovascular risk in the Polish adult population.
Results: Compared to age-matched healthy controls, women with premature CAD had a very high prevalence of traditional risk factors - hypercholesterolaemia (82% vs 68%), smoking (current and former) (81% vs 48%), and hypertension (68% vs 42%). Women with premature CAD had 4.3 times more often diabetes, 1.68 times smoking and 1.63 times hypertension compared to controls. At least one of five classical risk factors was present in 98.8% of patients, compared to 89% in controls, while 10% of patients vs 1.4% of controls had all five of them.
Conclusions: Classical risk factors are present in the vast majority of females with premature CAD - in 99% of them at least one CAD risk factor is present. Premature CAD is most frequently associated with smoking, hypertension and hyperlipidaemia.
Kardiol Pol 2010; 68, 9: 1032-1037
Get Citation

Keywords

premature coronary artery disease; cardiovascular risk factors; gender

About this article
Title

Prevalence of classical risk factors in Polish women with premature coronary artery disease

Journal

Kardiologia Polska (Polish Heart Journal)

Issue

Vol 68, No 9 (2010)

Pages

1032-1037

Published online

2010-09-21

Bibliographic record

Kardiol Pol 2010;68(9):1032-1037.

Keywords

premature coronary artery disease
cardiovascular risk factors
gender

Authors

Barbara Lubiszewska
Ewa Skóra
Mariusz Kruk
Grażyna Broda
Ewa Księżycka
Paweł Kurjata
Tomasz Zieliński
Rafał Płoski

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