open access

Vol 69, Supp. III (2011)
Review articles
Published online: 2011-11-24
Submitted: 2012-12-28
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Conditioning the heart in cardiac surgery

Marek A. Deja, Marcin Malinowski

open access

Vol 69, Supp. III (2011)
Review articles
Published online: 2011-11-24
Submitted: 2012-12-28

Abstract

Cardiac surgery is associated with ischaemic and reperfusion injury to the myocardium. It seems natural to seek a possibility of inducing the natural endoprotective mechanisms known as myocardial conditioning, including preconditioning, postconditioning, and remote conditioning. Still, in spite of almost 20 years of research in the field, we are far from routine widespread usage of these methods, with published reports describing quite various, and often contradictory results. Current review summarises the trials of using the conditioning in cardiac surgical practice including pharmacological manipulations to induce resistance to ischaemia-reperfusion.
Kardiol Pol 2011; 69, supl. III: 80–84

Abstract

Cardiac surgery is associated with ischaemic and reperfusion injury to the myocardium. It seems natural to seek a possibility of inducing the natural endoprotective mechanisms known as myocardial conditioning, including preconditioning, postconditioning, and remote conditioning. Still, in spite of almost 20 years of research in the field, we are far from routine widespread usage of these methods, with published reports describing quite various, and often contradictory results. Current review summarises the trials of using the conditioning in cardiac surgical practice including pharmacological manipulations to induce resistance to ischaemia-reperfusion.
Kardiol Pol 2011; 69, supl. III: 80–84
Get Citation

Keywords

cardiac surgery; ischaemia/reperfusion; ischaemic preconditioning; ischaemic postconditioning; remote preconditioning; pharmacological preconditioning

About this article
Title

Conditioning the heart in cardiac surgery

Journal

Kardiologia Polska (Polish Heart Journal)

Issue

Vol 69, Supp. III (2011)

Pages

80-84

Published online

2011-11-24

Keywords

cardiac surgery
ischaemia/reperfusion
ischaemic preconditioning
ischaemic postconditioning
remote preconditioning
pharmacological preconditioning

Authors

Marek A. Deja
Marcin Malinowski

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