open access

Vol 70, No 1 (2012)
Original articles
Published online: 2012-01-20
Submitted: 2012-12-28
Get Citation

Primary percutaneous angioplasty, thrombolysis and conservative treatment in low-risk patients with ST-elevation myocardial infarction: effects on short- and long-term mortality

Stefan Grajek, Aleksander Araszkiewicz, Maciej Lesiak, Marek Grygier, Małgorzata Pyda, Włodzimierz Skorupski, Przemysław Mitkowski, Artur Baszko
Kardiol Pol 2012;70(1):1-5.

open access

Vol 70, No 1 (2012)
Original articles
Published online: 2012-01-20
Submitted: 2012-12-28

Abstract

Background: Although primary coronary intervention (PCI) is currently regarded as the preferred reperfusion strategy in ST- -elevation myocardial infarction (STEMI), its superiority over thrombolysis has been documented mainly in high-risk patients. In low-risk patients, the difference seems to be not so significant.
Aim: To evaluate the early and late mortality in low-risk STEMI patients treated with thrombolysis, PCI, or conservatively.
Methods: From a total of 3,780 consecutive STEMI patients presenting within 24 h from symptom onset, 990 low-risk patients (age < 70 years old, Killip-Kimball class 1 at admission, non-anterior STEMI) were selected. The median follow-up duration was 18.3 (14.2–25.0) months. The patients were subdivided into three groups: group A (n = 465) — treated with PCI; group B (n = 289) — treated with thrombolysis; and group C (n = 236) — treated conservatively.
Results: In the whole study group 12 (1.21%) patients died; 30-day mortality in group A was 0.65%. In group B five out of 289 (1.73%) patients died, and in group C four out of 236 (1.69%) patients died. No significant differences in 30-day mortality between these three groups were found (p = 0.3). During the long-term follow-up, 37 (3.7%) of 990 patients died. In group A 18 (3.9%) patients died, in group B ten (3.4%) patients died, and in group C nine (3.8%) patients died (p = 0.96).
Conclusions: No significant differences in 30-day or long-term mortality rates between conservative therapy, PCI or thrombolysis groups in low-risk STEMI patients were observed.
Kardiol Pol 2012; 70, 1: 1–5

Abstract

Background: Although primary coronary intervention (PCI) is currently regarded as the preferred reperfusion strategy in ST- -elevation myocardial infarction (STEMI), its superiority over thrombolysis has been documented mainly in high-risk patients. In low-risk patients, the difference seems to be not so significant.
Aim: To evaluate the early and late mortality in low-risk STEMI patients treated with thrombolysis, PCI, or conservatively.
Methods: From a total of 3,780 consecutive STEMI patients presenting within 24 h from symptom onset, 990 low-risk patients (age < 70 years old, Killip-Kimball class 1 at admission, non-anterior STEMI) were selected. The median follow-up duration was 18.3 (14.2–25.0) months. The patients were subdivided into three groups: group A (n = 465) — treated with PCI; group B (n = 289) — treated with thrombolysis; and group C (n = 236) — treated conservatively.
Results: In the whole study group 12 (1.21%) patients died; 30-day mortality in group A was 0.65%. In group B five out of 289 (1.73%) patients died, and in group C four out of 236 (1.69%) patients died. No significant differences in 30-day mortality between these three groups were found (p = 0.3). During the long-term follow-up, 37 (3.7%) of 990 patients died. In group A 18 (3.9%) patients died, in group B ten (3.4%) patients died, and in group C nine (3.8%) patients died (p = 0.96).
Conclusions: No significant differences in 30-day or long-term mortality rates between conservative therapy, PCI or thrombolysis groups in low-risk STEMI patients were observed.
Kardiol Pol 2012; 70, 1: 1–5
Get Citation

Keywords

primary angioplasty; thrombolysis; acute myocardial infarction; prognosis

About this article
Title

Primary percutaneous angioplasty, thrombolysis and conservative treatment in low-risk patients with ST-elevation myocardial infarction: effects on short- and long-term mortality

Journal

Kardiologia Polska (Polish Heart Journal)

Issue

Vol 70, No 1 (2012)

Pages

1-5

Published online

2012-01-20

Bibliographic record

Kardiol Pol 2012;70(1):1-5.

Keywords

primary angioplasty
thrombolysis
acute myocardial infarction
prognosis

Authors

Stefan Grajek
Aleksander Araszkiewicz
Maciej Lesiak
Marek Grygier
Małgorzata Pyda
Włodzimierz Skorupski
Przemysław Mitkowski
Artur Baszko

Important: This website uses cookies. More >>

The cookies allow us to identify your computer and find out details about your last visit. They remembering whether you've visited the site before, so that you remain logged in - or to help us work out how many new website visitors we get each month. Most internet browsers accept cookies automatically, but you can change the settings of your browser to erase cookies or prevent automatic acceptance if you prefer.

By "Via Medica sp. z o.o." sp.k., Świętokrzyska 73 street, 80–180 Gdańsk, Poland

tel.:+48 58 320 94 94, faks:+48 58 320 94 60, e-mail: viamedica@viamedica.pl