Vol 60, No 4 (2004)
Other
Published online: 2005-12-12
Submitted: 2012-12-28
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Chronic heart failure. The relationship between increased activity of skeletal muscle ergoreceptors and reduced exercise tolerance

Agnieszka Kaczmarek, Ewa Jankowska, Tomasz Witkowski, Agnieszka Kuś-Klinowska, Beata Ponikowska, Krzysztof Reczuch, Ludmiła Borodulin-Nadzieja, Halina Hańczycowa, Waldemar Banasiak, Piotr Ponikowski
Kardiol Pol 2004;60(4):328-332.
Vol 60, No 4 (2004)
Other
Published online: 2005-12-12
Submitted: 2012-12-28

Abstract

Background: In chronic heart failure (CHF), skeletal muscle abnormalities may lead to the overactivation of ergoreceptors which in turn may cause sympathetic overactivation and increased ventilatory response to exercise.
Aim: To assess ergoreceptor reflex response to exercise and to evaluate whether ergoreceptor overactivity is related to the progression of CHF.
Methods: In 69 patients with CHF (66 males, mean age 62.7±11.6 years, NYHA class I/II/III/IV - 11/32/24/2 patients, respectively) and 24 controls without CHF (22 males, mean age 59±4.6 years) the ergoreflex contribution to the ventilatory and haemodynamic responses to exercise was evaluated. Moreover, in 13 patients with CHF, reproducibility of the measurements was assessed by repeating the test 1 to 7 days later.
Results: Enhanced ergoreflex effects on ventilation (1.9±1.6 vs 0.14±0.7 l/min, p

Abstract

Background: In chronic heart failure (CHF), skeletal muscle abnormalities may lead to the overactivation of ergoreceptors which in turn may cause sympathetic overactivation and increased ventilatory response to exercise.
Aim: To assess ergoreceptor reflex response to exercise and to evaluate whether ergoreceptor overactivity is related to the progression of CHF.
Methods: In 69 patients with CHF (66 males, mean age 62.7±11.6 years, NYHA class I/II/III/IV - 11/32/24/2 patients, respectively) and 24 controls without CHF (22 males, mean age 59±4.6 years) the ergoreflex contribution to the ventilatory and haemodynamic responses to exercise was evaluated. Moreover, in 13 patients with CHF, reproducibility of the measurements was assessed by repeating the test 1 to 7 days later.
Results: Enhanced ergoreflex effects on ventilation (1.9±1.6 vs 0.14±0.7 l/min, p
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Keywords

chronic heart failure - skeletal muscle ergoreceptors

About this article
Title

Chronic heart failure. The relationship between increased activity of skeletal muscle ergoreceptors and reduced exercise tolerance

Journal

Kardiologia Polska (Polish Heart Journal)

Issue

Vol 60, No 4 (2004)

Pages

328-332

Published online

2005-12-12

Bibliographic record

Kardiol Pol 2004;60(4):328-332.

Keywords

chronic heart failure - skeletal muscle ergoreceptors

Authors

Agnieszka Kaczmarek
Ewa Jankowska
Tomasz Witkowski
Agnieszka Kuś-Klinowska
Beata Ponikowska
Krzysztof Reczuch
Ludmiła Borodulin-Nadzieja
Halina Hańczycowa
Waldemar Banasiak
Piotr Ponikowski

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