open access

Vol 63, No 8 (2005)
Other
Published online: 2005-08-19
Submitted: 2012-12-28
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ORIGINAL ARTICLE
Influence of coronary artery bypass grafting performed in patients with unstable angina on left ventricular remodelling in medium-term follow-up

Ewa Gaszewska-Żurek, Paweł Żurek, Piotr Olszówka, Tomasz Kargul, Stanisław Woś, Michał Tendera
Kardiol Pol 2005;63(8):115-123.

open access

Vol 63, No 8 (2005)
Other
Published online: 2005-08-19
Submitted: 2012-12-28

Abstract

Introduction: Left ventricular remodelling is a process of change in size, shape, wall thickness and heart function, initiated by a noxious stimulus such as ischaemia. Methods of pharmacological and surgical inhibition or reversal of remodelling are being sought. Aim: To assess the influence of coronary artery bypass grafting on echocardiographic measures of left ventricular size and shape in medium-term follow-up. Methods: In a group of 30 patients three echocardiographic examinations were performed: before CABG operation, 3 months after and 20 months after the operation. Left ventricular area and volumes as well as indices of sphericity, thinning and expansion were calculated. Results: After the operation, left ventricular areas measured in short axis and in apical four-chamber view increased among patients with a history of myocardial infarction. Improvement in the sphericity index occurred after the operation in patients with a history of myocardial infarction in whom the ejection fraction before the operation was less than 50%. Conclusions: The left ventricular remodelling process progresses after coronary artery bypass grafting in patients with a history of myocardial infarction. Inhibition of remodelling may be expected in patients without myocardial infarction, with preserved left ventricular systolic function.

Abstract

Introduction: Left ventricular remodelling is a process of change in size, shape, wall thickness and heart function, initiated by a noxious stimulus such as ischaemia. Methods of pharmacological and surgical inhibition or reversal of remodelling are being sought. Aim: To assess the influence of coronary artery bypass grafting on echocardiographic measures of left ventricular size and shape in medium-term follow-up. Methods: In a group of 30 patients three echocardiographic examinations were performed: before CABG operation, 3 months after and 20 months after the operation. Left ventricular area and volumes as well as indices of sphericity, thinning and expansion were calculated. Results: After the operation, left ventricular areas measured in short axis and in apical four-chamber view increased among patients with a history of myocardial infarction. Improvement in the sphericity index occurred after the operation in patients with a history of myocardial infarction in whom the ejection fraction before the operation was less than 50%. Conclusions: The left ventricular remodelling process progresses after coronary artery bypass grafting in patients with a history of myocardial infarction. Inhibition of remodelling may be expected in patients without myocardial infarction, with preserved left ventricular systolic function.
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Keywords

left ventricular remodelling; ischaemic heart disease; CABG

About this article
Title

ORIGINAL ARTICLE
Influence of coronary artery bypass grafting performed in patients with unstable angina on left ventricular remodelling in medium-term follow-up

Journal

Kardiologia Polska (Polish Heart Journal)

Issue

Vol 63, No 8 (2005)

Pages

115-123

Published online

2005-08-19

Bibliographic record

Kardiol Pol 2005;63(8):115-123.

Keywords

left ventricular remodelling
ischaemic heart disease
CABG

Authors

Ewa Gaszewska-Żurek
Paweł Żurek
Piotr Olszówka
Tomasz Kargul
Stanisław Woś
Michał Tendera

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