open access

Vol 64, No 11 (2006)
Other
Published online: 2006-12-04
Submitted: 2012-12-28
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Original article
Prospective evaluation of glucose metabolism in patients undergoing coronary artery bypass grafting

Krzysztof Greberski, Przemysław Guzik, Henryk Wysocki, Ryszard Kalawski
Kardiol Pol 2006;64(11):1187-1193.

open access

Vol 64, No 11 (2006)
Other
Published online: 2006-12-04
Submitted: 2012-12-28

Abstract


Introduction: Disturbances of glucose metabolism are associated with increased risk of ischaemic heart disease (IHD). It is not uncommon that IHD and its complications precede diagnosis of glucose metabolism disturbances. Since publication of the American Diabetes Association’s 2004 Guidelines for the assessment of glucose metabolism, no prospective evaluation of prevalence of carbohydrate metabolism disorders in patients referred for coronary artery bypass grafting (CABG) has been performed.
Aim: Evaluation of prevalence of glucose balance disturbances in consecutive patients with stable IHD who underwent elective CABG procedures.
Methods: Prospective analysis of glucose metabolism was carried out on a group of 117 consecutive IHD patients (including 31 women) aged below 80 years, selected for elective CABG surgery. In all patients, history assessment and physical examination as well as basic biochemical studies and resting echocardiography were performed. Additionally, in all individuals without previous diagnosis of diabetes mellitus, oral glucose tolerance test (OGTT) was carried out.
Results: History analysis revealed glucose balance disturbances in 35 (29.9%) patients, including diabetes mellitus in 33 (28.2%) subjects and impaired glucose tolerance in 2 (1.7%) individuals. Based on OGTT results, among the remaining 82 (70.1%) subjects without previously known glucose metabolism disturbances 4 (3.4%) patients had abnormal fasting glycaemia, 32 (27.4%) subjects had impaired glucose tolerance, and diabetes mellitus was diagnosed in 12 (10.3%) individuals. No impaired glucose balance was found in only 34 (29.1%) examined subjects.
Conclusions: Over 70% of all patients undergoing elective CABG procedure presented various forms of carbohydrate metabolism disturbances that were not diagnosed previously. Thus, it seems that the assessment of glucose regulation should be mandatory in all patients undergoing elective CABG surgery.

Abstract


Introduction: Disturbances of glucose metabolism are associated with increased risk of ischaemic heart disease (IHD). It is not uncommon that IHD and its complications precede diagnosis of glucose metabolism disturbances. Since publication of the American Diabetes Association’s 2004 Guidelines for the assessment of glucose metabolism, no prospective evaluation of prevalence of carbohydrate metabolism disorders in patients referred for coronary artery bypass grafting (CABG) has been performed.
Aim: Evaluation of prevalence of glucose balance disturbances in consecutive patients with stable IHD who underwent elective CABG procedures.
Methods: Prospective analysis of glucose metabolism was carried out on a group of 117 consecutive IHD patients (including 31 women) aged below 80 years, selected for elective CABG surgery. In all patients, history assessment and physical examination as well as basic biochemical studies and resting echocardiography were performed. Additionally, in all individuals without previous diagnosis of diabetes mellitus, oral glucose tolerance test (OGTT) was carried out.
Results: History analysis revealed glucose balance disturbances in 35 (29.9%) patients, including diabetes mellitus in 33 (28.2%) subjects and impaired glucose tolerance in 2 (1.7%) individuals. Based on OGTT results, among the remaining 82 (70.1%) subjects without previously known glucose metabolism disturbances 4 (3.4%) patients had abnormal fasting glycaemia, 32 (27.4%) subjects had impaired glucose tolerance, and diabetes mellitus was diagnosed in 12 (10.3%) individuals. No impaired glucose balance was found in only 34 (29.1%) examined subjects.
Conclusions: Over 70% of all patients undergoing elective CABG procedure presented various forms of carbohydrate metabolism disturbances that were not diagnosed previously. Thus, it seems that the assessment of glucose regulation should be mandatory in all patients undergoing elective CABG surgery.
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Keywords

choroba niedokrwienna serca; pomostowanie aortalno-wieńcowe; zaburzenia metabolizmu glukozy ischaemic heart disease; coronary artery bypass grafting; glucose metabolism disturbances

About this article
Title

Original article
Prospective evaluation of glucose metabolism in patients undergoing coronary artery bypass grafting

Journal

Kardiologia Polska (Polish Heart Journal)

Issue

Vol 64, No 11 (2006)

Pages

1187-1193

Published online

2006-12-04

Bibliographic record

Kardiol Pol 2006;64(11):1187-1193.

Keywords

choroba niedokrwienna serca
pomostowanie aortalno-wieńcowe
zaburzenia metabolizmu glukozy ischaemic heart disease
coronary artery bypass grafting
glucose metabolism disturbances

Authors

Krzysztof Greberski
Przemysław Guzik
Henryk Wysocki
Ryszard Kalawski

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