open access

Vol 65, No 12 (2007)
Other
Published online: 2007-12-21
Submitted: 2012-12-28
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Original article
Economic evaluation of screening for familiar form of arrhythmogenic right ventricular cardiomyopathy in Poland

Ewa Kowalik, Elżbieta K. Włodarska, Olgierd Woźniak, Piotr Hoffman
Kardiol Pol 2007;65(12):1442-1446.

open access

Vol 65, No 12 (2007)
Other
Published online: 2007-12-21
Submitted: 2012-12-28

Abstract


Background:

Arrhythmogenic right ventricular cardiomyopathy (ARVC) is a myocardial disease associated with fibrofatty tissue replacement in heart muscle leading to arrhythmia, heart failure or sudden death (SCD) often being the first manifestation in probands. At least 50% of cases of ARVC are inherited.
Aim:

To evaluate costs and cost-effectiveness of diagnosis of the disease in asymptomatic relatives in Poland.
Methods:

239 asymptomatic subjects (mean age 35 years, 120 male) belonging to 42 families affected with ARVC were examined between May 2003 and May 2005. The costs of outpatient visits and additional diagnostic tests were included. Payer perspective was used.
Results:

In all individuals ECG and transthoracic echocardiography were performed. Magnetic resonance imaging and signal-averaged ECG were performed in 35 patients suspected of having ARVC. The diagnostic criteria for ARVC were fulfilled in 29 patients and 57 subjects were recognised borderline. Total costs of screening amounted to 71 090 PLN (approximately 20 000 euro). The average cost per one case of detected ARVC was 2451 PLN (approximately 680 euro).
Conclusions:

Costs of early detection of ARVC in individuals with a family history of the disease in Polish settings are low. Due the avilability of primary prevention of SCD the family screening in asymptomatic subjects is a cost-effective procedure.

Abstract


Background:

Arrhythmogenic right ventricular cardiomyopathy (ARVC) is a myocardial disease associated with fibrofatty tissue replacement in heart muscle leading to arrhythmia, heart failure or sudden death (SCD) often being the first manifestation in probands. At least 50% of cases of ARVC are inherited.
Aim:

To evaluate costs and cost-effectiveness of diagnosis of the disease in asymptomatic relatives in Poland.
Methods:

239 asymptomatic subjects (mean age 35 years, 120 male) belonging to 42 families affected with ARVC were examined between May 2003 and May 2005. The costs of outpatient visits and additional diagnostic tests were included. Payer perspective was used.
Results:

In all individuals ECG and transthoracic echocardiography were performed. Magnetic resonance imaging and signal-averaged ECG were performed in 35 patients suspected of having ARVC. The diagnostic criteria for ARVC were fulfilled in 29 patients and 57 subjects were recognised borderline. Total costs of screening amounted to 71 090 PLN (approximately 20 000 euro). The average cost per one case of detected ARVC was 2451 PLN (approximately 680 euro).
Conclusions:

Costs of early detection of ARVC in individuals with a family history of the disease in Polish settings are low. Due the avilability of primary prevention of SCD the family screening in asymptomatic subjects is a cost-effective procedure.
Get Citation

Keywords

cardiomyopathy; screening; cost-effectiveness

About this article
Title


Original article
Economic evaluation of screening for familiar form of arrhythmogenic right ventricular cardiomyopathy in Poland

Journal

Kardiologia Polska (Polish Heart Journal)

Issue

Vol 65, No 12 (2007)

Pages

1442-1446

Published online

2007-12-21

Bibliographic record

Kardiol Pol 2007;65(12):1442-1446.

Keywords

cardiomyopathy
screening
cost-effectiveness

Authors

Ewa Kowalik
Elżbieta K. Włodarska
Olgierd Woźniak
Piotr Hoffman

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