open access

Vol 65, No 2 (2007)
Other
Published online: 2007-02-23
Submitted: 2012-12-28
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Original article
Early and long-term outcomes after surgical treatment in patients with aortic stenosis and severe left ventricular heart failure without concomitant coronary artery disease with respect to preoperative mean transvalvular pressure gradient

Dariusz Zakrzewski, Ewa Orłowska-Baranowska, Tomasz Sitko, Grzegorz Religa, Piotr Hoffman, Janina Stępińska
Kardiol Pol 2007;65(2):153-157.

open access

Vol 65, No 2 (2007)
Other
Published online: 2007-02-23
Submitted: 2012-12-28

Abstract


Introduction: There are limited data on early and long-term prognosis in patients after aortic valve replacement who have left ventricular dysfunction, reduced ejection fraction (EF) ≤35% and no concomitant coronary artery disease.
Aim: To assess the prognosis in this group of patients depending on the mean aortic gradient (MAG) value.
Methods: This study involved 60 patients with severe aortic stenosis and EF ≤35%. Patients with coronary artery disease, more than moderate aortic regurgitation and any other valvular lesion were excluded. Patients were divided into two groups based on the MAG values: group I included patients with MAG ≤35 mmHg, and group II included patients with MAG >35 mmHg.
Results: Early mortality after aortic valve replacement was 14.2% in group I, and 5.1% in group II. During a mean follow-up of 48 months mortality in groups I and II was 16.6% and 2.6%, respectively. In the follow-up period, a significant functional improvement according to NYHA scale as well as significant decrease of left ventricular dimensions and increase of EF was observed in both groups of patients.
Conclusions:Patients with severe aortic stenosis, left ventricular ejection fraction 35 mmHg should be classified as the group of slightly increased risk.

Abstract


Introduction: There are limited data on early and long-term prognosis in patients after aortic valve replacement who have left ventricular dysfunction, reduced ejection fraction (EF) ≤35% and no concomitant coronary artery disease.
Aim: To assess the prognosis in this group of patients depending on the mean aortic gradient (MAG) value.
Methods: This study involved 60 patients with severe aortic stenosis and EF ≤35%. Patients with coronary artery disease, more than moderate aortic regurgitation and any other valvular lesion were excluded. Patients were divided into two groups based on the MAG values: group I included patients with MAG ≤35 mmHg, and group II included patients with MAG >35 mmHg.
Results: Early mortality after aortic valve replacement was 14.2% in group I, and 5.1% in group II. During a mean follow-up of 48 months mortality in groups I and II was 16.6% and 2.6%, respectively. In the follow-up period, a significant functional improvement according to NYHA scale as well as significant decrease of left ventricular dimensions and increase of EF was observed in both groups of patients.
Conclusions:Patients with severe aortic stenosis, left ventricular ejection fraction 35 mmHg should be classified as the group of slightly increased risk.
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Keywords

aortic stenosis; left ventricular failure; postoperative mortality

About this article
Title

Original article
Early and long-term outcomes after surgical treatment in patients with aortic stenosis and severe left ventricular heart failure without concomitant coronary artery disease with respect to preoperative mean transvalvular pressure gradient

Journal

Kardiologia Polska (Polish Heart Journal)

Issue

Vol 65, No 2 (2007)

Pages

153-157

Published online

2007-02-23

Bibliographic record

Kardiol Pol 2007;65(2):153-157.

Keywords

aortic stenosis
left ventricular failure
postoperative mortality

Authors

Dariusz Zakrzewski
Ewa Orłowska-Baranowska
Tomasz Sitko
Grzegorz Religa
Piotr Hoffman
Janina Stępińska

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