open access

Vol 65, No 3 (2007)
Other
Published online: 2007-03-26
Submitted: 2012-12-28
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Original article
Percutaneous valve repair for mitral regurgitation using the Carillon™ Mitral Contour System™. Description of the method and case report

Tomasz Siminiak, Ludwik Firek, Olga Jerzykowska, Piotr Kałmucki, Maciej Wołoszyn, Piotr Smuszkiewicz, Rafał Link
Kardiol Pol 2007;65(3):272-278.

open access

Vol 65, No 3 (2007)
Other
Published online: 2007-03-26
Submitted: 2012-12-28

Abstract

Mitral regurgitation may result from left ventricular dilatation and cause progression of heart failure. Percutaneous techniques for mitral valve repair are under development. Techniques utilizing a trans-coronary venous approach exploit the anatomical relationship between the mitral annulus and the venous system of the heart. The coronary sinus, great cardiac vein and the origin of the anterior interventricular vein surround the posterior mitral annulus. This enables percutaneous approaches to annuloplasty for mitral regurgitation. Devices can be implanted into the coronary veins that modify the shape and size of the mitral annulus. We present a case of ischaemic mitral regurgitation successfully treated by use of a percutaneous approach, the Carillon™ Mitral Contour System™. Significant reduction of the mitral regurgitation jet was observed. The patient was discharged 4 days after the procedure. During the follow-up visits, the patient showed an improved general condition and increased exercise capacity. Procedural steps are shown in detail and the current status of the coronary sinus based technique is discussed. Percutaneous techniques for mitral valve repair may be an attractive alternative to cardiac surgery in heart failure patients with secondary mitral regurgitation. The Carillon™ Mitral Contour System™ is under ongoing clinical evaluation in the AMADEUS trial.

Abstract

Mitral regurgitation may result from left ventricular dilatation and cause progression of heart failure. Percutaneous techniques for mitral valve repair are under development. Techniques utilizing a trans-coronary venous approach exploit the anatomical relationship between the mitral annulus and the venous system of the heart. The coronary sinus, great cardiac vein and the origin of the anterior interventricular vein surround the posterior mitral annulus. This enables percutaneous approaches to annuloplasty for mitral regurgitation. Devices can be implanted into the coronary veins that modify the shape and size of the mitral annulus. We present a case of ischaemic mitral regurgitation successfully treated by use of a percutaneous approach, the Carillon™ Mitral Contour System™. Significant reduction of the mitral regurgitation jet was observed. The patient was discharged 4 days after the procedure. During the follow-up visits, the patient showed an improved general condition and increased exercise capacity. Procedural steps are shown in detail and the current status of the coronary sinus based technique is discussed. Percutaneous techniques for mitral valve repair may be an attractive alternative to cardiac surgery in heart failure patients with secondary mitral regurgitation. The Carillon™ Mitral Contour System™ is under ongoing clinical evaluation in the AMADEUS trial.
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Keywords

mitral regurgitation; percutaneous techniques; ischaemic heart disease; coronary veins

About this article
Title

Original article
Percutaneous valve repair for mitral regurgitation using the Carillon™ Mitral Contour System™. Description of the method and case report

Journal

Kardiologia Polska (Polish Heart Journal)

Issue

Vol 65, No 3 (2007)

Pages

272-278

Published online

2007-03-26

Bibliographic record

Kardiol Pol 2007;65(3):272-278.

Keywords

mitral regurgitation
percutaneous techniques
ischaemic heart disease
coronary veins

Authors

Tomasz Siminiak
Ludwik Firek
Olga Jerzykowska
Piotr Kałmucki
Maciej Wołoszyn
Piotr Smuszkiewicz
Rafał Link

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