open access

Vol 65, No 9 (2007)
Other
Published online: 2007-10-03
Submitted: 2012-12-28
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Original article
Restrictive filling pattern predicts pulmonary hypertension and is associated with increased BNP levels and impaired exercise capacity in patients with heart failure

Ewa Straburzyńska-Bugaj, Andrzej Szyszka, Olga Trojnarska, Andrzej Cieśliński
Kardiol Pol 2007;65(9):1049-1055.

open access

Vol 65, No 9 (2007)
Other
Published online: 2007-10-03
Submitted: 2012-12-28

Abstract

Background: Left ventricular (LV) diastolic dysfunction is a common finding in patients with systolic heart failure (HF). Severe diastolic dysfunction, which is defined as LV restrictive filling pattern (RFP), is associated with more severe HF, increased sympathetic activity and reduced exercise capacity. It has also been shown to be a predictor of lower survival rate in patients with HF.
Aim:
To evaluate associations between LV diastolic RFP and BNP levels, systolic pulmonary pressure and exercise capacity in patients with clinically stable HF.
Methods: In 56 patients with HF and low LVEF a standard echocardiographic study and cardiopulmonary exercise test were performed. Levels of BNP using RIA method were also measured.
Results: Restrictive filling pattern (E/A >2 or 1< E/A

Abstract

Background: Left ventricular (LV) diastolic dysfunction is a common finding in patients with systolic heart failure (HF). Severe diastolic dysfunction, which is defined as LV restrictive filling pattern (RFP), is associated with more severe HF, increased sympathetic activity and reduced exercise capacity. It has also been shown to be a predictor of lower survival rate in patients with HF.
Aim:
To evaluate associations between LV diastolic RFP and BNP levels, systolic pulmonary pressure and exercise capacity in patients with clinically stable HF.
Methods: In 56 patients with HF and low LVEF a standard echocardiographic study and cardiopulmonary exercise test were performed. Levels of BNP using RIA method were also measured.
Results: Restrictive filling pattern (E/A >2 or 1< E/A
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Keywords

niewydolność serca; dysfunkcja rozkurczowa; BNP; nadciśnienie płucne; test spiroergometryczny

About this article
Title

Original article
Restrictive filling pattern predicts pulmonary hypertension and is associated with increased BNP levels and impaired exercise capacity in patients with heart failure

Journal

Kardiologia Polska (Polish Heart Journal)

Issue

Vol 65, No 9 (2007)

Pages

1049-1055

Published online

2007-10-03

Bibliographic record

Kardiol Pol 2007;65(9):1049-1055.

Keywords

niewydolność serca
dysfunkcja rozkurczowa
BNP
nadciśnienie płucne
test spiroergometryczny

Authors

Ewa Straburzyńska-Bugaj
Andrzej Szyszka
Olga Trojnarska
Andrzej Cieśliński

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